ECH1 Polyclonal Antibody

SKU: E-AB-18979

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ECH1

Target Synonym: 4)-dienoyl-CoA isomerase;5)-Delta(2;Delta(3 5) Delta(2 4) dienoyl CoA isomerase;Delta(3 5) Delta(2 4) dienoyl CoA isomerase mitochondrial;Delta(3;Delta3 5 delta2 4 dienoyl CoA isomerase;Dienoyl CoA isomerase;ECH 1;Ech1;ECH1;Enoyl Coenzyme A hydratase 1;Enoyl Coenzyme A hydratase 1 peroxisomal;HPXEL;mitochondrial;MS1034;Peroxisomal enoyl CoA hydratase 1;Peroxisomal enoyl coenzyme A hydratase like protein

Research Areas: Cancer;Cardiovascular;Metabolism;Signal transduction;Tags and Cell markers

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q13011

Accession:

Background: This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

Concentration: 0.6 mg/mL

Immunogen: Fusion protein of human ECH1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:300

Calculated MW: 36 kDa

ObservedMW: Refer to figures