CXCL12/SDF1 Polyclonal Antibody

SKU: E-AB-40578

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CXCL12

Target Synonym: Cxcl12; SDF-1

Research Areas: Immunology;Microbiology;Cardiovascular

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9QZD1

Accession:

Background: The stromal cell derived factor 1 (SDF1/CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1/CXCL12 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1/CXCL12 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1/CXCL12 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1/CXCL12 isoforms (SDF1/CXCL12α and SDF1/CXCL12β) that have different properties and biological activities. Additional isoforms of SDF1/CXCL12 have been reported.

Concentration: 1 mg/mL

Immunogen: Recombinant Rat CXCL12 protein expressed by E.coli.

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: WB 1:2000-4000

Calculated MW: 10kDa

ObservedMW: 10kDa