ZGPAT antibody , Cat. # FNab09634

SKU: FNab09634

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA.

Immunogen:zinc finger, CCCH-type with G patch domain

Synonyms:ZGPAT, ZC3HDC9, ZC3H9, KIAA1847, GPATCH6

Observed MW:57 kDa

Uniprot ID:Q8N5A5

Reactivity:Human, Mouse

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:5000

Gene ID:84619

Research Area:Metabolism