YEATS4 Antibody - Cat. #: CSB-PA105916

SKU: CSB-PA105916

Size :100ul

Clone Number:

Aliases:4930573H17Rik antibody; B230215M10Rik antibody; GAS 41 antibody; Gas41 antibody; glioma amplified sequence 41 antibody; Glioma-amplified sequence 41 antibody; glioma-amplified sequence-41 antibody; gliomaamplified sequence 41 antibody; gliomaamplified sequence41 antibody; NUBI 1 antibody; NuBI-1 antibody; NuBI1 antibody; NuMA binding protein 1 antibody; NuMA-binding protein 1 antibody; YAF9 antibody; YEATS domain containing 4 antibody; YEATS domain containing4 antibody; YEATS domain-containing protein 4 antibody; YEATS4 antibody; YETS4_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95619

Immunogen:Synthesized peptide derived from internal of Human GAS41.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.

Fischer U., Hum. Mol. Genet. 6:1817-1822(1997).
Harborth J., J. Biol. Chem. 275:31979-31985(2000).
Ota T., Nat. Genet. 36:40-45(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:YEATS4

Research Areas:Epigenetics and Nuclear Signaling