YBX1 Antibody - Cat. #: CSB-PA992754

SKU: CSB-PA992754

Size :50ul

Clone Number:

Aliases:BP 8 antibody; CBF-A antibody; CCAAT binding transcription factor I subunit A antibody; CCAAT-binding transcription factor I subunit A antibody; CSDA2 antibody; CSDB antibody; DBPB antibody; DNA binding protein B antibody; DNA-binding protein B antibody; EFI-A antibody; Enhancer factor I subunit A antibody; MDR NF1 antibody; MGC104858 antibody; MGC110976 antibody; MGC117250 antibody; NSEP 1 antibody; NSEP1 antibody; Nuclease sensitive element binding protein 1 antibody; Nuclease-sensitive element-binding protein 1 antibody; p50 antibody; Q15905 antibody; Y-box binding protein 1 antibody; Y-box transcription factor antibody; Y-box-binding protein 1 antibody; YB 1 antibody; YB-1 antibody; YBOX1_HUMAN antibody; YBX 1 antibody; ybx1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P67809

Immunogen:Synthetic peptide of Human YBX1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:YBX1

Research Areas:Epigenetics and Nuclear Signaling;Developmental biology?Tags & Cell Markers;Stem cells