XRCC6 Monoclonal Antibody

SKU: BT-MCA2290

Size:100μL

Background:The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:XRCC6

applications:WB, IHC, ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:2F7F5

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:XRCC6

Immunogen:Purified recombinant fragment of human XRCC6 (AA: 6-214) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):69.8kDa

UniProt accession:P12956

Synonyms:ML8, KU70, TLAA, CTC75, CTCBF, G22P1

GeneID:2547