XRCC1 Monoclonal Antibody

SKU: BT-MCA4201

Size:100μL

Background:The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:XRCC1

applications:WB, IHC, FCM

Reactivity:

Clonality:Monoclonal

Clone ID:4D10D3

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:XRCC1

Immunogen:Purified recombinant fragment of human XRCC1 (AA: 1-150) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):69.5kDa

UniProt accession:P18887

Synonyms:RCC, SCAR26

GeneID:7515