XPC Polyclonal Antibody

SKU: E-AB-53352

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:XPC

Target Synonym:DNA repair protein complementing XP C cells;DNA repair protein complementing XP-C cells;DNA repair protein complementing XPC cells ;p125;RAD4;Xeroderma pigmentosum complementation group C;Xeroderma pigmentosum group C complementing protein;Xeroderma pigmentosum group C protein;Xeroderma pigmentosum group C-complementing protein;Xeroderma pigmentosum group III;XP 3;XP C;XP group C;XP3;Xpc;XPC gene;XPC;XPCC

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q01831

Accession:

Background:The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

Concentration:0.66 mg/mL

Immunogen:Synthetic peptide of human XPC

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:30-1:150

Calculated MW:

ObservedMW: