WDR24 antibody , Cat. # FNab09488

SKU: FNab09488

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:As a component of the GATOR subcomplex GATOR2, functions as an activator of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238, PubMed:27166823). Inhibits the GATOR1 subcomplex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway(PubMed:23723238). Functions downstream of and is regulated by amino acid sensors like SESN2(PubMed:26449471, PubMed:26586190). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux(PubMed:27166823).

Immunogen:WD repeat domain 24

Synonyms:C16orf21, DKFZp434F054, JFP7, WD repeat domain 24, WDR24

Observed MW:102 kDa

Uniprot ID:Q96S15

Reactivity:Human, Mouse

Tested Application:ELISA, WB, IHC, IF

Recommended dilution:WB: 1:500-1:5000; IP: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:20-1:200

Gene ID:84219

Research Area:Cell Division and Proliferation