Visfatin Monoclonal Antibody

SKU: BT-MCA3808

Size:100μL

Background:Visfatin, a newly identified adipocytokine ,which is predominantly secreted from visceral adipose tissue both in humans and mice . Visfatin corresponds to a protein identified previously as pre-B cell colony-enhancing factor (PBEF). Visfatin exerted insulin-mimetic effects in cultured cells, various insulin-sensitive tissues such as liver, muscle, and fat ,and lowered plasma glucose levels in mice. Mice heterozygous for a targeted mutation in the visfatin gene had modestly higher levels of plasma glucose relative to wild-type littermates. visfatin binds to and activates the insulin receptor. Which may lead to new insights into glucose homeostasis and/or new therapies for metabolic disorders such as diabetes.

Research_area:Others

Target_protein:Visfatin

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:4E11C9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:Visfatin

Immunogen:Purified recombinant fragment of Visfatin expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P43490

Synonyms:PBEF, MGC117256

GeneID:10135