Vav3(Phospho Tyr173) Polyclonal Antibody

SKU: BT-AP15438

Size:100μL

Background:This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research_area:Signal transduction; Cancer

Target_protein:VAV3

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Guanine nucleotide exchange factor VAV3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):97776

UniProt accession:Human: Q9UKW4; Mouse: Q9R0C8

Synonyms:Guanine nucleotide exchange factor VAV3; VAV3; Guanine nucleotide exchange factor VAV3; VAV-3

GeneID:Human: 10451; Mouse: 57257