USP14 Polyclonal Antibody

SKU: E-AB-18519

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: USP14

Target Synonym: Deubiquitinating enzyme 14;TGT;tRNA guanine transglycosylase 60 kD subunit;tRNA guanine transglycosylase;Ubiquitin carboxyl terminal hydrolase 14;Ubiquitin carboxyl-terminal hydrolase 14;Ubiquitin specific peptidase 14;Ubiquitin specific processing protease 14;Ubiquitin specific protease 14;Ubiquitin thiolesterase 14;Ubiquitin-specific-processing protease 14;UBP14;USP 14;USP14

Research Areas: Cancer;Cell Biology;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P54578

Accession:

Background: This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Concentration: 0.7 mg/mL

Immunogen: Fusion protein of human USP14

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 56 kDa

ObservedMW: Refer to figures