UMPS Polyclonal Antibody

SKU: E-AB-52440

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:UMPS

Target Synonym:ODC;OMPdecase;OPRT;OPRTase;Orotate phosphoribosyl transferase and orotidine 5' decarboxylase;Orotate phosphoribosyltransferase;Orotate phosphoribosyltransferase phosphoribosyltransferase;Orotidine 5' phosphate decarboxylase;Orotidine 5''-phosphate decarboxylase;RP11-71H17.9;UMP synthase;Umps;UMPS;Uridine 5' monophosphate synthase;Uridine monophosphate synthetase

Research Areas:Epigenetics and Nuclear Signaling;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P11172

Accession:

Background:This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Concentration:0.7 mg/mL

Immunogen:Fusion protein of human UMPS

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:WB 1:500-1:2000;IHC 1:30-1:150

Calculated MW:52 kDa

ObservedMW:Refer to figures