UBE2B Rabbit Polyclonal Antibody

SKU: BT-AP05368

Size:100μL

Background:The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes| or E1s| ubiquitin-conjugating enzymes| or E2s| and ubiquitin-protein ligases| or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse| rat| and rabbit homologs| which indicates that this enzyme is highly conserved in eukaryotic evolution.

Research_area:Epigenetics and nuclear signaling; Cell biology; Metabolism; Cancer

Target_protein:UBE2B

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:UBE2B

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):16720

UniProt accession:Human: P63146; Mouse: P63147; Rat: P63149

Synonyms:UBE2B

GeneID:Human: 7320; Mouse: 22210; Rat: 81816