Txnip Antibody, HRP conjugated - Cat. #: CSB-PA803849LB01MO

SKU: CSB-PA803849LB01MO

Size :50ug

Clone Number:

Aliases:Txnip antibody; Vdup1 antibody; Thioredoxin-interacting protein antibody; Vitamin D3 up-regulated protein 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Mus musculus (Mouse)

UniProt ID:Q8BG60

Immunogen:Recombinant Mouse Thioredoxin-interacting protein (1-397AA)

Raised in:Rabbit

Species Reactivity:Mouse

Tested Applications:ELISA

Background:May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Txnip

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism; Signal transduction