TRIP13 antibody , Cat. # FNab08997

SKU: FNab08997

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks(DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes(By similarity).

Immunogen:thyroid hormone receptor interactor 13

Synonyms:16E1 BP, 16E1BP, PCH2, TR interacting protein 13, TRIP 13, TRIP13

Observed MW:49 kDa

Uniprot ID:Q15645

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IP, IHC

Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:50-1:500

Gene ID:9319

Research Area:Signal Transduction