TNK2 Polyclonal Antibody

SKU: E-AB-12226

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:TNK2

Target Synonym:Acetate kinase 1;Acetokinase 1;ACK 1;ACK;ACK-1;ACK1;ACK1;Activated Cdc42 associated kinase 1;Activated CDC42 kinase 1;Activated p21cdc42Hs kinase;FLJ44758;FLJ45547;p21cdc42Hs;TNK 2;TNK2;Tyrosine kinase non receptor 2;Tyrosine kinase non receptor protein 2;Tyrosine kinase non-receptor protein 2

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q07912

Accession:

Background:This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.

Concentration:0.6 mg/mL

Immunogen:Synthetic peptide of human TNK2

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:1000-1:5000;IHC 1:50-1:200

Calculated MW:119kDa

ObservedMW: