TNFRSF1A Antibody - Cat. #: CSB-PA973584

SKU: CSB-PA973584

Size :100ul

Clone Number:

Aliases:CD120a antibody; FPF antibody; MGC19588 antibody; p55 antibody; p55-R antibody; p60 antibody; TBP1 antibody; TBPI antibody; TNF R antibody; TNF R55 antibody; TNF-R1 antibody; TNF-RI antibody; TNFAR antibody; TNFR-I antibody; TNFR1 antibody; TNFR55 antibody; TNFR60 antibody; TNFRI antibody; TNFRSF1a antibody; TNR1A_HUMAN antibody; Tumor necrosis factor receptor 1 antibody; Tumor necrosis factor receptor superfamily, member 1A antibody; Tumor necrosis factor receptor type 1 antibody; Tumor necrosis factor receptor type I antibody; Tumor necrosis factor-binding protein 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P19438

Immunogen:Synthesized peptide derived from Internal of Human TNF receptor-1.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

Jennifer Adjodha, AACR Meeting Abstracts, Apr 2006; 2006: 1028.
Kewu Huang, J Appl Physiol, Apr 2007; 102: 1632 - 1639.
Kiyoshi Asada, AACR Meeting Abstracts, Apr 2005; 2005: 202.
Elaine K Green, J. Med. Genet., Aug 2000; 37: 581.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TNFRSF1A

Research Areas:Cancer?Cardiovascular?Cell biology;Immunology;Signal transduction?Stem cells