TNFRSF11B Monoclonal Antibody

SKU: BT-MCA2893

Size:100μL

Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Research_area:Cardiovascular

Target_protein:TNFRSF11B

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:5A11

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:TNFRSF11B

Immunogen:Purified recombinant fragment of human TNFRSF11B expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):60kDa

UniProt accession:O00300

Synonyms:OPG, TR1, OCIF, MGC29565, TNFRSF11B

GeneID:4982