TNFAIP1 antibody , Cat. # FNab08817

SKU: FNab08817

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:2H3

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.

Immunogen:tumor necrosis factor, alpha-induced protein 1(endothelial)

Synonyms:BACURD2, EDP1

Observed MW:36 kDa

Uniprot ID:Q13829

Reactivity:Human

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:1000-1:6000; IHC: 1:50-1:600

Gene ID:7126

Research Area:Metabolism