TNFAIP1 Antibody - Cat. #: CSB-PA094566

SKU: CSB-PA094566

Size :100ul

Clone Number:

Aliases:TNFAIP1 antibody; BACURD2 antibody; EDP1BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 antibody; hBACURD2 antibody; BTB/POZ domain-containing protein TNFAIP1 antibody; Protein B12 antibody; Tumor necrosis factor antibody; alpha-induced protein 1 antibody; endothelial antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13829

Immunogen:Synthesized peptide derived from internal of Human TNAP1.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.

Wolf F.W., J. Biol. Chem. 267:1317-1326(1992).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TNFAIP1

Research Areas:Signal transduction