TNF-α Polyclonal Antibody

SKU: E-AB-68252

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:TNF-α

Target Synonym:TNF;DIF;TNF-alpha;TNFA;TNFSF2;TNLG1F;TNF alpha

Research Areas:Cancer;Cardiovascular;Metabolism;Immunology;Signaling transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC;IF

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P01375

Accession:

Background:This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Concentration:1 mg/mL

Immunogen:Recombinant fusion protein of human TNF

Buffer:PBS with 0.05% proclin300,50% glycerol,pH7.3.

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:50-1:200;IF 1:50-1:200

Calculated MW:25kDa

ObservedMW:Refer to figures