TMEM123 Antibody - Cat. #: CSB-PA292200

SKU: CSB-PA292200

Size :50ul

Clone Number:

Aliases:TMEM123 antibody; KCT3 antibody; PSEC0111 antibody; UNQ641/PRO1271 antibody; Porimin antibody; Keratinocytes-associated transmembrane protein 3 antibody; KCT-3 antibody; Pro-oncosis receptor inducing membrane injury antibody; Transmembrane protein 123 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8N131

Immunogen:Fusion protein of Human TMEM123

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:30-1:150

Background:This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TMEM123

Research Areas:Cancer;Cell biology