TLE1 antibody , Cat. # FNab08719

SKU: FNab08719

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 24 months(Avoid repeated freeze / thaw cycles.)

Background:Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Immunogen:transducin-like enhancer of split 1

Synonyms:E(Sp1) homolog, ESG, ESG1, GRG1, TLE1

Observed MW:83kDa

Uniprot ID:Q04724

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Gene ID:7088

Research Area:Signal Transduction, Metabolism, Cancer, Immunology, Developmental biology