TIMP2 Antibody - Cat. #: CSB-PA411062

SKU: CSB-PA411062

Size :50ul

Clone Number:

Aliases:CSC 21K antibody; CSC-21K antibody; CSC21K antibody; Metalloproteinase inhibitor 2 antibody; Metalloproteinase inhibitor 2 precursor antibody; TIMP 2 antibody; TIMP metallopeptidase inhibitor 2 antibody; TIMP-2 antibody; TIMP2 antibody; TIMP2_HUMAN antibody; Tissue Inhibitor of Metalloproteinase 2 antibody; Tissue inhibitor of metalloproteinases 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P16035

Immunogen:Fusion protein of Human TIMP2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TIMP2

Research Areas:Cancer?Cardiovascular?Cell biology;Signal transduction