TIMP1 Polyclonal Antibody

SKU: D-AB-10195L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:TIMP1

Target Synonym:Clgi;Collagenase inhibitor;Collagenase inhibitor;Human;EPA;EPO;Erythroid Potentiating Activity;Erythroid-potentiating activity;Fibroblast collagenase inhibitor;FLJ90373;HCI;Human Collagenase Inhibitor;Metalloproteinase inhibitor 1;Metalloproteinase inhibitor 1 precursor;OTTHUMP00000023214;TIMP 1;TIMP;TIMP metallopeptidase inhibitor 1;TIMP-1;Timp1;TIMP1 protein;TIMP1;Tissue Inhibitor of Metalloproteinase 1;Tissue inhibitor of metalloproteinases 1;Tissue inhibitor of metalloproteinases;Ttissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor

Research Areas:Cancer;Cell Biology;Cardiovascular;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Mouse

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P12032

Accession:

Background:This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Concentration:1 mg/mL

Immunogen:Recombinant Mouse Timp1 protein expressed by E.coli

Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:500-1:1000

Calculated MW:23kDa

ObservedMW:30kDa