TIM-3/HAVCR2 Polyclonal Antibody

SKU: E-AB-60706

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:TIM-3/HAVCR2

Target Synonym:HAVCR2;CD366;HAVcr-2;KIM-3;TIM3;TIMD-3;TIMD3;Tim-3

Research Areas:Cancer;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q8TDQ0

Accession:

Background:The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Concentration:1mg/mL

Immunogen:Recombinant fusion protein of human TIM-3/HAVCR2 (NP_116171.3).

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification method:Affinity purification

Dilution:IHC 1:50-1:200

Calculated MW:

ObservedMW: