TIGAR Antibody - Cat. #: CSB-PA202764

SKU: CSB-PA202764

Size :50ul

Clone Number:

Aliases:6-bisphosphatase TIGAR antibody; C12ORF5 antibody; chromosome 12 open reading frame 5 antibody; FR2BP antibody; Fructose-2,6-bisphosphatase TIGAR antibody; Fructose-2,6-bisphosphate 2-phosphatase antibody; Probable fructose 2,6 bisphosphatase TIGAR antibody; Probable fructose-2 antibody; tigar antibody; TIGAR_HUMAN antibody; TP53 induced glycolysis and apoptosis regulator antibody; TP53 induced glycolysis regulatory phosphatase antibody; TP53-induced glycolysis and apoptosis regulator antibody; Transactivated by NS3TP2 protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NQ88

Immunogen:Synthetic peptide of Human TIGAR

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:20-1:100

Background:This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TIGAR

Research Areas:Cell biology