GeneBio Systems
Tie1 Monoclonal Antibody
Tie1 Monoclonal Antibody
SKU:AN200055P
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Size::20μL
Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping:Ice bag
Exp date:12 months
Category ID_II:Primary Antibodies
Category ID_III:Monoclonal Antibodies
Abbreviation:Tie1
Target Synonym:JTK;Tyrosine-Protein Kinase Receptor Tie;TIE1;JTK14;TIE;Tyrosine-Protein Kinase Receptor Tie-1;Tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Research Areas:Signal Transduction;Stem Cells;Cancer;Cardiovascular;Developmental Biology
Conjugation:Unconjugated
Host:Mouse
Species reactivity:Human
Application:IHC-P
Isotype:IgG2b
Clonality:Monoclonal
Clone NO.:9D4
UNIProt ID:P35590
Accession:
Background:This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie1 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Concentration:1 mg/mL
Immunogen:Recombinant Human Tie1 Protein
Buffer:0.2 μm filtered solution in PBS
Purification method:Protein A
Dilution:IHC-P 1:50-1:200;
Calculated MW:
ObservedMW:
