TCF3 Antibody - Cat. #: CSB-PA079787

SKU: CSB-PA079787

Size :100ul

Clone Number:

Aliases:AGM8 antibody; bHLHb21 antibody; Class B basic helix-loop-helix protein 21 antibody; E12 antibody; E2A antibody; E2A immunoglobulin enhancer binding factors E12/E47 antibody; E47 antibody; Helix loop helix protein HE47 antibody; Immunoglobulin enhancer-binding factor E12/E47 antibody; Immunoglobulin transcription factor 1 antibody; ITF1 antibody; Kappa-E2-binding factor antibody; MGC129647 antibody; MGC129648 antibody; Negative vitamin D response element binding protein antibody; NOL1-TCF3 fusion antibody; TCF-3 antibody; Tcf3 antibody; TFE2_HUMAN antibody; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) antibody; Transcription factor 3 antibody; transcription factor 3 variant 3 antibody; Transcription factor E2-alpha antibody; Transcription factor ITF-1 antibody; VDIR antibody; VDR interacting repressor antibody; vitamin D receptor-interacting repressor antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P15923

Immunogen:Synthesized peptide derived from C-terminal of Human TCF3.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Transcriptional regulator. Involved in the initiation of neuronal differentiation. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Binds to IEB1 and IEB2, which are short DNA sequences in the insulin gene transcription control region.

Kamps M.P., Cell 60:547-555(1990).
Nourse J., Cell 60:535-545(1990).
Grimwood J., Nature 428:529-535(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TCF3

Research Areas:Epigenetics and Nuclear Signaling;Stem cells