TAOK3 Antibody - Cat. #: CSB-PA935138

SKU: CSB-PA935138

Size :100ul

Clone Number:

Aliases:CTCL tumor antigen HD CL 09 antibody; CTCL-associated antigen HD-CL-09 antibody; Cutaneous T cell lymphoma tumor antigen HD CL 09 antibody; Cutaneous T-cell lymphoma-associated antigen HD-CL-09 antibody; Dendritic cell derived protein kinase antibody; Dendritic cell-derived protein kinase antibody; DKFZp666H245 antibody; DPK antibody; FLJ31808 antibody; hKFC A antibody; hKFC-A antibody; JIK antibody; JNK/SAPK inhibitory kinase antibody; JNK/SAPK-inhibitory kinase antibody; Jun kinase inhibitory kinase antibody; Jun kinase-inhibitory kinase antibody; KDS antibody; Kinase from chicken homolog A antibody; MAP3K18 antibody; Serine kinase antibody; Serine/threonine-protein kinase TAO3 antibody; STE20 like kinase antibody; TAO kinase 3 antibody; TAOK3 antibody; TAOK3_HUMAN antibody; Thousand and one amino acid protein 3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H2K8

Immunogen:Synthesized peptide derived from internal of Human TAOK3.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).

Tassi E., J. Biol. Chem. 274:33287-33295(1999).
Zhang W., Biochem. Biophys. Res. Commun. 274:872-879(2000).
Yustein J.T., Oncogene 22:6129-6141(2003).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TAOK3

Research Areas:Epigenetics and Nuclear Signaling;Signal transduction