TAB3 Polyclonal Antibody

SKU: E-AB-11380

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:TAB3

Target Synonym:MAP3K7IP 3;Mitogen-activated protein kinase kinase kinase 7-interacting protein 3;NAP1;NF-kappa-B-activating protein 1;NFkB activating protein 1;TAB-3;Tab3;TAB3;TAK1 binding protein 3;TAK1-binding protein 3;TGF-beta-activated kinase 1 and MAP3K7-binding protein 3;TGF-beta-activated kinase 1-binding protein 3

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Immunology;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q8N5C8

Accession:

Background:The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.

Concentration:0.2 mg/mL

Immunogen:Recombinant protein of human TAB3

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:1000-1:5000

Calculated MW:79kDa

ObservedMW: