SYNE3 Antibody - Cat. #: CSB-PA293250

SKU: CSB-PA293250

Size :100ul

Clone Number:

Aliases:C14orf49 antibody; Chromosome 14 open reading frame 49 antibody; FLJ25605 antibody; MGC75267 antibody; Nesp3 antibody; Nesprin 3 antibody; Nesprin-3 antibody; NET53 antibody; Nuclear Envelope Spectrin Repeat Protein 3 antibody; Spectrin Repeat Containing, Nuclear Envelope Family Member 3 antibody; SYNE3 antibody; SYNE3_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q6ZMZ3

Immunogen:Synthesized peptide derived from internal of Human C14orf49.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.

Li W.B., Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
Heilig R., Nature 421:601-607(2003).
Ota T., Nat. Genet. 36:40-45(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SYNE3

Research Areas:Signal transduction