SUPV3L1 antibody , Cat. # FNab08397

SKU: FNab08397

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome(mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded(ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.

Immunogen:suppressor of var1, 3-like 1(S. cerevisiae)

Synonyms:SUV3

Observed MW:70-80 kDa

Uniprot ID:Q8IYB8

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IP, WB

Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000

Gene ID:

Research Area:Metabolism