SUN1 antibody , Cat. # FNab08392

SKU: FNab08392

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.1% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration(INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes(NPCs)(By similarity). Required for efficient localization of SYNE4 in the nuclear envelope(By similarity).

Immunogen:unc-84 homolog A(C. elegans)

Synonyms:KIAA0810, UNC84A

Observed MW:90 kDa

Uniprot ID:O94901

Reactivity:Human

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:5000

Gene ID:6821

Research Area:Cell Division and Proliferation