STK40 Antibody - Cat. #: CSB-PA158011

SKU: CSB-PA158011

Size :50ul

Clone Number:

Aliases:STK40 antibody; SGK495 antibody; SHIK antibody; Serine/threonine-protein kinase 40 antibody; EC 2.7.11.1 antibody; SINK-homologous serine/threonine-protein kinase antibody; Sugen kinase 495 antibody; SgK495 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8N2I9

Immunogen:Fusion protein of Human STK40

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:50-1:200

Background:STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NF?B and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NF?B-mediated gene transcription. Similarly, overexpression of STK40 inhibits NF?B activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:STK40

Research Areas:Epigenetics and Nuclear Signaling;Cell biology;Signal transduction