STK10 Antibody - Cat. #: CSB-PA889950

SKU: CSB-PA889950

Size :100ul

Clone Number:

Aliases:LOK antibody; Lymphocyte oriented kinase antibody; Lymphocyte-oriented kinase antibody; PRO2729 antibody; Serine threonine protein kinase 10 antibody; Serine/threonine-protein kinase 10 antibody; STK10 antibody; STK10_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O94804

Immunogen:Synthesized peptide derived from internal of Human STK10.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.

Kuramochi S., Immunogenetics 49:369-375(1999).
Ota T., Nat. Genet. 36:40-45(2004).
Schmutz J., Nature 431:268-274(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:STK10

Research Areas:Signal transduction