Gene Bio Systems
STIM2 Antibody, HRP conjugated - Cat. #: CSB-PA022830LB01HU
STIM2 Antibody, HRP conjugated - Cat. #: CSB-PA022830LB01HU
SKU:CSB-PA022830LB01HU
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Size :50ug
Clone Number:
Aliases:FLJ39527 antibody; KIAA1482 antibody; STIM 2 antibody; STIM2 antibody; STIM2_HUMAN antibody; Stromal interaction molecule 2 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens (Human)
UniProt ID:Q9P246
Immunogen:Recombinant Human Stromal interaction molecule 2 protein (471-656AA)
Raised in:Rabbit
Species Reactivity:Human
Tested Applications:ELISA
Background:Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. Regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI3. May inhibit STIM1-mediated Ca(2+) influx.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjugate:HRP
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:STIM2
Research Areas:Signal transduction
