STAT6 Monoclonal Antibody

SKU: BT-MCA2138

Size:100μL

Background:STAT6 protein is a transcription factor activated by cytokines, particularly interleukin 4 and IL 13. (STAT6-/-) were found to be deficient in IL 4 mediated functions including Th2 helper T cell differentiation, expression of cell surface markers, T cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL 4 mediated proliferation. STAT6 mRNA has been detected in peripheral bloodlymphocytes, colon, intestine, ovary, prostate,thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.

Research_area:Signal Transduction

Target_protein:STAT6

applications:WB, ICC

Reactivity:Human, Mouse, Rat, Monkey

Clonality:Monoclonal

Clone ID:7D3

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:STAT6

Immunogen:Purified recombinant fragment of human STAT6 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):94kDa

UniProt accession:P42226

Synonyms:STAT6B, STAT6C, D12S1644, IL-4-STAT, STAT6

GeneID:6778