Stat1(Phospho Tyr701) Polyclonal Antibody

SKU: BT-AP01644

Size:100μL

Background:The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors| STAT family members are phosphorylated by the receptor associated kinases| and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha| interferon-gamma| EGF| PDGF and IL6. This protein mediates the expression of a variety of genes| which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Research_area:Epigenetics and nuclear signaling; Cancer; Signal transduction; Microbiology

Target_protein:STAT1

applications:IF, ICC, WB, IHC-p, IP, ELISA

Reactivity:Human, Mouse, Rat, Monkey

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Signal transducer and activator of transcription 1-alpha/beta

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):87335

UniProt accession:Human: P42224; Mouse: P42225

Synonyms:Signal transducer and activator of transcription 1-alpha/beta; STAT1; Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3 components p91/p84

GeneID:Human: 6772