SSTR2 Antibody, FITC conjugated - Cat. #: CSB-PA022725LC01HU

SKU: CSB-PA022725LC01HU

Size :50ug

Clone Number:

Aliases:Somatostatin receptor type 2 antibody; SRIF-1 antibody; SRIF1 antibody; SS-2-R antibody; SS2-R antibody; SS2R antibody; SSR2_HUMAN antibody; SST2 antibody; SSTR2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P30874

Immunogen:Recombinant Human Somatostatin receptor type 2 protein (304-369AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SSTR2

Research Areas:Neuroscience; Cancer; Metabolism