SphK2(Phospho Thr614) Polyclonal Antibody

SKU: BT-AP14421

Size:100μL

Background:This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research_area:Signal transduction; Metabolism; Cell biology; Cancer

Target_protein:SPHK2

applications:IHC-p, IF, WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Sphingosine kinase 2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):69217

UniProt accession:Human: Q9NRA0; Mouse: Q9JIA7

Synonyms:Sphingosine kinase 2; SPHK2; Sphingosine kinase 2; SK 2; SPK 2

GeneID:Human: 56848; Mouse: 56632