speB Antibody - Cat. #: CSB-PA676488LA01SBAF

SKU: CSB-PA676488LA01SBAF

Size :50ug

Clone Number:

Aliases:speB antibody; M28_Spy1721 antibody; Streptopain antibody; EC 3.4.22.10 antibody; Exotoxin type B antibody; SPE B antibody; Streptococcal cysteine proteinase antibody; Streptococcus peptidase A antibody; SPP antibody

Product Type:Polyclonal Antibody

Immunogen Species:Streptococcus pyogenes serotype M28

UniProt ID:Q48R29

Immunogen:Recombinant Streptococcus pyogenes serotype M28 Streptopain protein (146-398AA)

Raised in:Rabbit

Species Reactivity:Streptococcus pyogenes serotype M28

Tested Applications:ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background:Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:speB

Research Areas:Others