SPARC Antibody - Cat. #: CSB-PA189204

SKU: CSB-PA189204

Size :100ul

Clone Number:

Aliases:AA517111 antibody; Basement membrane protein 40 antibody; Basement-membrane protein 40 antibody; BM 40 antibody; BM-40 antibody; BM40 antibody; Cysteine rich protein antibody; hm:zeh0062 antibody; MGC128090 antibody; OI17 antibody; ON antibody; Osteonectin antibody; Secreted acidic cystein rich glycoprotein antibody; Secreted protein acidic and cysteine rich antibody; Secreted protein acidic and rich in cysteine antibody; Secreted protein acidic cysteine rich (osteonectin) antibody; Secreted protein acidic cysteine rich antibody; SPARC antibody; SPRC antibody; SPRC_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P09486

Immunogen:Peptide sequence around aa.52~56 (V-G-E-F-D) derived from Human SPARC.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca2+ with a low affinity and an EF-hand loop that binds a Ca2+ ion with a high affinity.

Kelm R.J. Jr., Mann K.G. Blood 75:1105-1113(1990)
Wewer U.M., Albrechtsen R., Fisher L.W. Am. J. Pathol. 132:345-355(1988)
Kuhn C., Mason R.J.Am. J. Pathol. 147:1759-1769(1995)

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SPARC

Research Areas:Cancer?Cardiovascular?Cell biology?Developmental biology;Signal transduction?Stem cells