Sp3 (Acetyl Lys551) Rabbit Polyclonal Antibody

SKU: BT-AP12731

Size:100μL

Background:This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains| and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene| and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms| resulting from the use of alternate downstream translation initiation sites| have also been noted. A related pseudogene has been identified on chromosome 13.

Research_area:Epigenetics and nuclear signaling

Target_protein:SP3

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Sp3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):85910

UniProt accession:Human: Q02447; Mouse: O70494

Synonyms:Sp3 ;Acetyl Lys551; Transcription factor Sp3; SPR-2

GeneID:Human: 6670; Mouse: 20687