SOD1 Monoclonal Antibody

SKU: BT-MCA2229

Size:100μL

Background:SOD1 (superoxide dismutase 1, soluble), also known as ALS. The protein binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. Rare transcript variants have been reported for this gene.

Research_area:Signal Transduction

Target_protein:SOD1

applications:WB, ICC, FCM

Reactivity:Human, Mouse

Clonality:Monoclonal

Clone ID:6F5

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:SOD1

Immunogen:Purified recombinant fragment of human SOD1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):18kDa

UniProt accession:P00441

Synonyms:ALS, SOD, ALS1, IPOA, homodimer

GeneID:6647