SOCS3 Antibody - Cat. #: CSB-PA938450

SKU: CSB-PA938450

Size :50ul

Clone Number:

Aliases:ATOD4 antibody; CIS 3 antibody; CIS-3 antibody; CIS3 antibody; Cish3 antibody; Cytokine induced SH2 protein 3 antibody; Cytokine-inducible SH2 protein 3 antibody; E2a Pbx1 target gene in fibroblasts 10 antibody; EF 10 antibody; MGC71791 antibody; SOCS 3 antibody; SOCS-3 antibody; Socs3 antibody; SOCS3_HUMAN antibody; SSI 3 antibody; SSI-3 antibody; SSI3 antibody; STAT induced STAT inhibitor 3 antibody; STAT-induced STAT inhibitor 3 antibody; Suppressor of cytokine signaling 3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O14543

Immunogen:Fusion protein of Human SOCS3

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

Background:This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SOCS3

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Immunology?Metabolism;Signal transduction?Stem cells