SOCS1 Polyclonal Antibody

SKU: E-AB-70245

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:SOCS1

Target Synonym:CISH 1;CISH1;Cytokine inducible SH2 protein 1;JAB;JAK binding protein;JAK-binding protein;Janus kinase binding protein;SOCS 1;SOCS-1;Socs1;SOCS1;SSI 1;SSI-1;SSI1;STAT induced STAT inhibitor 1;STAT-induced STAT inhibitor 1;Suppressor of cytokine signaling 1;Supressor of cytokine signalling 1;TEC interacting protein 3;Tec-interacting protein 3;TIP 3;TIP-3;TIP3

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Immunology;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:O35716,Q9QX78

Accession:

Background:This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Concentration:0.89 mg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse SOCS1

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:IHC 1:200-1:800

Calculated MW:

ObservedMW: