Smad2 Rabbit pAb

SKU: EA241

Size: 100μL

Source:Rabbit

Applications:WB, IHC

Reactivity:Human, Rat, Mouse

Dilution:WB 1:1,000-2,000 IHC 1:100-200

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Polyclonal

Isotype:IgG

Concentration:1mg/mL

Observed_band(KD):60kDa

Human_gene_id:4087

Human_swiss_prot_no:Q157976

Subcellular_location:Cytoplasm, Nucleus

Other_name:hMAD2 antibody, JV18 antibody, MAD antibody, MADH2 antibody, MGC22139 antibody

Background:SMAD2 is a protein that in humans is encoded by the SMAD2 gene. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. SMAD2 mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein.