SLC4A11 Antibody - Cat. #: CSB-PA231998

SKU: CSB-PA231998

Size :100ul

Clone Number:

Aliases:Bicarbonate transporter related protein 1 antibody; Bicarbonate transporter-related protein 1 antibody; BTR1 antibody; CDPD antibody; CHED2 antibody; Corneal endothelial dystrophy 2 autosomal recessive antibody; dJ794I6.2 antibody; FECD4 antibody; MGC126418 antibody; MGC126419 antibody; NaBC1 antibody; S4A11_HUMAN antibody; Slc4a11 antibody; Sodium bicarbonate transporter-like protein 11 antibody; Sodium borate cotransporter 1 antibody; Sodium coupled borate cotransporter 1 antibody; Solute carrier family 4 member 11 antibody; Solute carrier family 4 sodium bicarbonate transporter like member 11 antibody; Solute carrier family 4 sodium borate transporter member 11 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8NBS3

Immunogen:Synthesized peptide derived from internal of Human SLC4A11.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Transporter which plays an important role in sodium-mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into the thin descending limb of Henle loop to allow countercurrent multiplication by osmotic equilibration By similarity. Involved in borate homeostasis. In the absence of borate, it functions as a Na+ and OH-(H+) channel. In the presence of borate functions as an electrogenic Na+ coupled borate cotransporter.

Parker M.D., Biochem. Biophys. Res. Commun. 282:1103-1109(2001).
Deloukas P., Nature 414:865-871(2001).
Ota T., Nat. Genet. 36:40-45(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SLC4A11

Research Areas:Neuroscience?Cancer;Metabolism;Signal transduction